教育背景
2007.09~2012.07 中國科學院,理化技術研究所碩博連讀,獲博士學位
2003.09~2007.07 北京師範大學,化學學院,獲學士學位
工作經曆
2019.08~至今 澳门京葡娱乐网,澳门京葡娱乐网, 副教授
2014.07~2019.08 贛南師範大學,澳门京葡娱乐网, 副教授
2012.07~2014.07 中國科學院理化技術研究所,助理研究員
榮譽與獎勵
2020年,入選内蒙古自治區第十批“草原英才”
2018年,入選江西省科技創新傑出青年人才
研究領域
課題組網站:https://www.x-mol.com/groups/Wang_Jianguo
1. 光電功能材料
2. 疾病診斷與治療
3. 化學/生物傳感器。
教學
主講大學化學、分析化學實驗等
研究項目
1. 國家自然科學基金地區科學基金,觸發式自降解分子與光敏劑分子的複合體系用于靶向光動力抗癌的活性研究,2017.01- 2020.12,主持。
2. 國家自然科學基金青年基金項目,利用上轉換納米顆粒構築近紅外激發的钌(II)多吡啶類光活化化療藥物,2014.01-2016.12,主持。
3. 第十批“草原英才”,2020.01-2022.12,主持。
4. 澳门京葡娱乐网科研人才引進“學術骨幹”,2020-2022,主持。
5. 内蒙古自治區自然科學基金面上項目,聚集誘導發光特性熒光分子的設計合成及緻病菌鑒别、光動力抗菌研究,2020.01-2022.12,主持。
6. 江西省自然科學傑出青年基金項目,利用聚集誘導發光現象開發可激活turn-on型癌症早期熒光診斷新方法,2018.01-2020.12,主持。
7. 江西省自然科學基金青年基金項目,利用四苯乙烯類AIE分子與葫蘆脲[7]形成的超分子結構構築選擇性識别精胺的探針,2017.01-2018.12,主持。
8. 江西省自然科學基金青年基金項目,利用上轉換納米顆粒構築近紅外激發的光控釋放一氧化碳的藥物,2015.01-2016.06,主持。
9. 江西省教育廳科技項目,利用四苯乙烯的聚集熒光檢測尿液中的脂多糖,2016.1-2017.06,主持。
10. 贛州市科技創新人才計劃項目,2019.01-2021.12,主持。
11. 中國科學院光化學轉換與功能材料重點實驗室開放課題,利用上轉換納米顆粒構築近紅外激發的光控釋放一氧化碳的藥物,2015.06- 2016.06,主持。
代表性成果
發表SCI期刊學術論文37篇,其中以第一或通訊作者在Anal. Chem., Adv. Opt. Mater., Chem. Commun.等國際著名期刊上發表論文25篇,申請發明專利10項,已授權發明專利8項;參與編寫《Handbook of Aggregation-Induced Emission》(Wiley Press)英文專著第11章。在國内外高水平學術會議上做邀請/口頭報告10餘次。
論文:(近五年部分代表性論文)
1. Guoyu Jiang, Chunbin Li, Qingfang Lai, Xiang Liu, Qingqing Chen, Pengfei Zhang, Jianguo Wang*, Ben Zhong Tang*, An Easily Available Ratiometric AIE Probe for Peroxynitrite in vitro and in vivo Imaging, Sens. Actuators B: Chem., 2021, 329, 129223. (SCI一區)
2. Chunbin Li, Guoyu Jiang, Xiang Liu, Qingfang Lai, Miaomiao Kang, Dong Wang, Pengfei Zhang, Jianguo Wang*, Ben Zhong Tang*, An Easily Available Ratiometric AIE Probe for Nitroxyl Visualization in vitro and in vivo Imaging, Mater. Chem. Front., 2021, 5, 1817-1823. (HOT Article) (SCI一區)
3. Guoyu Jiang, Chunbin Li, Xiang Liu, Qingqing Chen, Xiaokang Li, Xinggui Gu, Qingfang Lai, Jianguo Wang*, Lipid droplet‐targetable fluorescence guided photodynamic therapy of cancer cells with an activatable AIE‐active fluorescent probe for hydrogen peroxide, Adv. Opt. Mater., 2020, 8, 2001119. (SCI一區)
4. Jianguo Wang, Wenping Zhu, Chunbin Li, Pengfei Zhang, Guoyu Jiang*, Guangle Niu*, Ben Zhong Tang*, Mitochondria-targeting NIR fluorescent probe for rapid, highly sensitive and selective visualization of nitroxyl in live cells, tissues and mice, Sci. China Chem., 2020, 63, 282-289. (SCI一區)
5. Qiang Wang, Chunbin Li, Qingqing Chen, Pengfei Zhang, Dong Wang, Miaomiao Kang, Guoyu Jiang*, Jianguo Wang*, Lysosome-targeting red-emitting aggregation-induced emission probe with large stokes shift for light-up in situ visualization of β‑N‑acetylhexosaminidase. Anal. Chem., 2019, 91, 12611-12614. (SCI一區)
6. Jianguo Wang, Chunbin Li, Qingqing Chen, Hongfeng Li, Lihua Zhou, Xing Jiang, Mengxue Shi, Pengfei Zhang*, Guoyu Jiang*, Ben Zhong Tang*, An easily available ratiometric reaction-based AIE probe for carbon monoxide light-up imaging, Anal. Chem., 2019, 91, 9388-9392. (SCI一區)
7. Jianguo Wang, Wenping Zhu, Guangle Niu, Guoyu Jiang*, Qingqing Chen, Pei Gao, Yongdong Li, Guanxin Zhang, Xiaolin Fan, Ben Zhong Tang*, Selectively light-up hydrogen peroxide in hypoxic cancer cells with a novel fluorescent probe, Chem. Commun., 2018, 54, 13957-13960. (SCI一區)
8. Jianguo Wang, Lik-Kuen Ma, Jiachen Huang, Ming Chen, Zitong Liu, Guoyu Jiang*, He Yan*, Side-chain effect of perylene diimide tetramer-based non-fullerene acceptors for improving the performance of organic solar cells, Mater. Chem. Front., 2018, 2, 2104-2108. (2018年第三季度最受歡迎文章)
9. Guoyu Jiang, Wenping Zhu, Qingqing Chen, Xinbo Li, Guanxin Zhang, Yongdong Li*, Xiaolin Fan, Jianguo Wang*, Selective fluorescent probes for spermine and 1-adamantanamine based on the supramolecular structure formed between AIE-active molecule and cucurbit[n]urils. Sens. Actuators B: Chem., 2018, 261, 602-607. (SCI一區)
10. Jianguo Wang, Qingqing Chen, Na Tian, Wenping Zhu, Hang Zou, Xiaokang Li, Xiaolin Fan, Guoyu Jiang*, Ben Zhong Tang*, A fast responsive, highly selective and light-up fluorescent probe for two-photon imaging of carboxylesterase in living cells. J. Mater. Chem. B., 2018, 6, 1595-1599. (SCI二區)
11. Guoyu Jiang, Guanjie Zeng, Wenping Zhu, Yongdong Li, Xiaobiao Dong, Guanxin Zhang, Xiaolin Fan, Jianguo Wang*, Yongquan Wu*, Ben Zhong Tang*, A selective and light-up fluorescent probe for β-galactosidase activity detection and imaging in living cells based on an AIE tetraphenylethylene derivative, Chem. Commun., 2017, 53, 4505-4508. (SCI一區)
12. Guoyu Jiang, Xiang Liu, Qingqing Chen, Guanjie Zeng, Yongquan Wu, Xiaobiao Dong, Guanxin Zhang, Yongdong Li*, Xiaolin Fan, Jianguo Wang*, A new tetraphenylethylene based AIE probe for light-up and discriminatory detection of Cys over Hcy and GSH, Sens. Actuators B: Chem., 2017, 252, 712–716. (SCI一區)
13. Guoyu Jiang, Jianguo Wang*, Yang Yang, Guanxin Zhang*, Yaling Liu, He Lin, Guilan Zhang, Yongdong Li*, Xiaolin Fan, Fluorescent turn-on sensing of bacterial lipopolysaccharide in artificial urine sample with sensitivity down to nanomolar by tetraphenylethylene based aggregation induced emission molecule, Biosens. Bioelectron., 2016, 85, 62-67. (SCI一區)
專利:
1. 王建國,姜國玉,吳勇權,範小林,李勳,具有聚集誘導熒光增強特性的氟離子傳感器的合成及應用,專利号:ZL 201610323833.9。
2. 王建國,姜國玉,朱溫平,吳勇權,範小林,一種基于聚集誘導發光原理用于選擇性檢測半胱氨酸的熒光試劑的合成及應用,專利号:ZL 201710153023.X。
3. 王建國,姜國玉,吳勇權,範小林,一種基于聚集誘導熒光增強特性用于選擇性識别ATP的熒光探針、合成方法及其應用,專利号:ZL 201710143038.8。
4. 王建國,姜國玉,陳青青,李勳,範小林,一種羧酸酯酶熒光探針及其制備方法和應用,專利号:ZL 201810129535.7。
5. 王建國,姜國玉,吳勇權,範小林,具有聚集誘導熒光增強特性的β-半乳糖苷酶傳感器的合成及應用,專利号:ZL 201610538734.4。
6. 王建國,姜國玉,王強,一種氨基己糖酶熒光探針及其制備方法及應用,專利号:201910541339.5。
7. 王建國,姜國玉,劉祥,一種兼具雙氧水檢測和光動力殺傷癌細胞活性的熒光探針及其制備方法和應用,專利号:201910997394.5。
8. 王建國,姜國玉,朱溫平,一種具有雙光子和近紅外發光特性的亞硝酰氫熒光探針及其制備方法和應用,專利号:201910157417.1。
9. 王建國,姜國玉,李純斌,一種具有聚集誘導發光特性的比率型一氧化碳熒光探針的設計合成及應用,專利号:ZL201910299561.9。
10. 王建國,姜國玉,王強,一種9,10-二(N-(2,3-二羟丙基)丙酰胺基)蒽的制備方法,專利号:201910127803.6。