趙文傑
副教授 碩士生導師
辦公室:南校區實驗樓A309
郵箱:zhaowenjie@imu.edu.cn
教育背景
2009.09-2011.06:湖南大學 澳门京葡娱乐网,研究生/碩士
2012.09-2017.04:湖南大學 澳门京葡娱乐网,研究生/博士
工作經曆
2011.07-2012.06: 天津凱萊英醫藥集團 助理研究員
2017.07-2018.07: 山西醫科大學 基礎醫學院 講師
2018.08-2018.12: 澳门京葡娱乐网 澳门京葡娱乐网 講師
2018.12-2021.12: 澳门京葡娱乐网 澳门京葡娱乐网 副研究員
2022.01--至今: 澳门京葡娱乐网 澳门京葡娱乐网 副教授
榮譽與獎勵
Ø内蒙古自治區第十批“草原英才”入選者(2020年)
Ø澳门京葡娱乐网“學術骨幹”入選者(2018年)
研究領域
Ø 疾病信号分子響應光學傳感器設計;
Ø 生物膜相關細胞生理過程熒光傳感研究;
Ø 外泌體蛋白信号轉導機理研究。
教學
主講澳门京葡娱乐网 本科生《儀器分析》、《分析化學實驗》、《環境化學》、《大學化學》、通識課《化學與現代生活》
研究生《高等分析化學》
研究項目
Ø 國家自然科學基金,單分子力譜成像及定量細胞表面多糖-凝集素相互作用,2024/01-2027/12,主持。
Ø 國家自然科學基金,外泌體中亞磺酸化蛋白識别熒光探針構建及成像應用研究,2020/01-2023/12,主持。
Ø 自治區第十批“草原英才”工程團隊和人選獎補資金,2020.01-2021.12,主持,已結題。
Ø 内蒙古自然科學基金,激活式熒光監控雙效應介導快速靈敏釋放體系構建及其調控活體血糖水平研究,2019/01-2021/12,主持,已結題。
Ø 澳门京葡娱乐网2019年引進高層次人才科研啟動金,2019/01-2021/01,主持。
代表性成果
學術論文:
(1) Zhirong Li; Lulu Zhang; Zhanzhong Wang; Xiongli Kang; Huiying Jin; Wenjie Zhao*; Jun Zhang*; Haiquan Su; Quantification of Phosphatidylserine Molecules on the Surface of Individual Cells Using Single-Molecule Force Spectroscopy, Analytical Chemistry, 2024, 96:676-684.
(2) Zhirong Li, Jiandong Jia*, Wenjie Zhao*, Leilei Jiang, Wenfei Tian. Seawater as supplemental moisture: The effect of Co-hydrothermal carbonization products obtained from chicken manure and cornstalk. Journal of Environmental Management 2023; 345:118819.
(3) Haofei Zhou, Ye Yuan, Zhexu Wang, Zexin Ren, Mixia Hu, JingKun Lu, Hongxia Gao, Cheng Pan, Wenjie Zhao*, Baohua Zhu*. Co-delivery of doxorubicin and quercetin by Janus hollow silica nanomotors for overcoming multidrug resistance in breast MCF-7/Adr cells. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2023, 658: 130654.
(4) Xiaomei Yang, Zhirong Li, Jun Zhang*, Wenjie Zhao*. Identification of two SPRY isoforms SPRY1 and SPRY3 by atomic force microscopy at the single-molecule level. Analyst, 2022, 147: 5694-5700.
(5) Yanxia Nan, Qiulan Zhou, Wenjie Zhao*, YanbingLu*, Weijian Xu*, In vivo imaging of hypoxia generation stimulated by testosterone using a micelle-based near-infrared fluorescent probe, Sensors & Actuators: B. Chemical, 2019, 288: 543–551.
(6) Yanxia Nan, Wenjie Zhao*, Ningbo Li, Zhiwu Liang, Xinhua Xu*, Chemiluminescence- triggered fluorophore release: Approach for in vivo fluorescence imaging of hydrogen peroxide, Sensors & Actuators: B. Chemical, 2019, 281: 296–302.
(7) Wenjie Zhao, Yinhui Li, Sheng Yang*, Yun Chen, Jing Zheng, Changhui Liu, Zhihe Qing, Jishan Li, and Ronghua Yang*, Target-Activated Modulation of Dual-Color and Two-Photon Fluorescence of Graphene Quantum Dots for in Vivo Imaging of Hydrogen Peroxide, Analytical Chemistry, 2016, 88: 4833-4840.
(8) Wenjie Zhao, Sheng Yang, Jinfeng Yang, Jishan Li, Jing Zheng, Zhihe Qing, and Ronghua Yang*, Visual Biopsy by Hydrogen Peroxide-induced Signal Amplification, Analytical Chemistry, 2016, 88: 10728-10735.
(9) Ningbo Li*, Lingxiao Wang, Haojiang Wang, Jie Qiao, Wenjie Zhao*, XinhuaXu*, Zhiwu Liang, Synthesis and structure of an air-stable bis(pentamethylcyclopentadienyl) zirconium pentafluorbezenesulfonate and its application in catalytic epoxide ring-opening reactions, Tetrahedron, 2018, 74: 1033-1039.
(10) Yanxia Nan, Yu Gu, Qiulan Zhou, Wenjie Zhao *, Jun Zhang*. Ultra-low background signaling cascade amplifiers for in vivo fluorescence imaging of hydroxyl radical production induced by testosterone. New Journal of Chemistry, 2021, 45, 15536.
(11) Yanxia Nan, Yu Gu, Zhen Liu, Qiulan Zhou, Wenjie Zhao*, Weijian Xu*. Versatile quantitative biopsy: an approach for cost-effective detection of hydrogen peroxide in tissue specimens. New Journal of Chemistry., 2021, 45, 4311.
(* Corresponding author)
招生計劃
本課題組可招收碩士生及科研助理,歡迎對分析化學及化學生物傳感感興趣的同學咨詢聯系。個人簡曆發送至此郵箱:zhaowenjie@imu.edu.cn